The global burden of Occupational Health (OH) issues is considerable. Fatal and non-fatal work-related injuries and illnesses worldwide equate to a cost of approximately €2680 billion, equivalent to 4% of the global GDP or the entire GDP of Great Britain.[i] Consequently, organisations, their workforce, and society have to bear a substantial cost. This new whitepaper discusses the value of Occupational Health (OH) from a global perspective and provides a synthesis of global evidence on the effectiveness of OH interventions and cost effectiveness. The paper demonstrates that Occupational Health services have a clear value: they improve the health of the working population; contribute to the prevention of work-related illnesses; prevent avoidable sickness absence through the provision of early interventions for those who develop a health condition; and increase the efficiency and productivity of organisations. They can also play a major part in protecting and revitalising the global economy.